TargetMol

N3PT

Product Code:
 
TAR-T12158
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
N3PT is a potent and selective inhibitor of transketolase(TK) with IC50 of 22 nM for Apo-TK)
CAS:
13860-66-7
Formula:
C13H19Cl2N3OS
Molecular Weight:
336.28
Purity:
0.98
SMILES:
Cl.[Cl-].Cc1c(CCO)sc[n+]1Cc1ccc(C)nc1N

References

1. Jeno Gyuris, May Han, Ronan C, N3-pyridyl-thiamine and its use in cancer treatments. Patent Numeber: WO2005094803 A2 2. Thomas AA, De Meese J, Le Huerou Y, Non-charged thiamine analogs as inhibitors of enzyme transketolase. Bioorg Med Chem Lett. 2008 Jan 15;18(2):509-12.