TargetMol

BMS-816336

Product Code:
 
TAR-T12614L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12614L-50mg50mg£1,163.00
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TAR-T12614L-100mg100mg£1,934.00
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Further Information

Bioactivity:
BMS-816336 is a novel, orally bioavailable inhibitor, and potent against human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with an IC50 of 3.0 nM[1].
CAS:
1009583-20-3
Formula:
C21H27NO3
Molecular Weight:
341.44
Pathway:
Metabolism
Purity:
0.98
SMILES:
OC1CN(C1)C(=O)CC1(C2CC3CC1CC(C2)C3O)c1ccccc1
Target:
Dehydrogenase

References

1. Ye XY, et al. Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11?-Hydroxysteroid Dehydrogenase Type 1 Inhibitor. J Med Chem. 2017 Jun 22;60(12):4932-4948.