TargetMol

Voruciclib hydrochloride

Product Code:
 
TAR-T13309
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T13309-5mg5mg£303.00
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TAR-T13309-50mg50mg£1,163.00
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Quantity:
TAR-T13309-100mg100mg£1,564.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Voruciclib hydrochloride is an orally active and selective inhibitor of CDK (Ki: 0.626 nM-9.1 nM).
CAS:
1000023-05-1
Formula:
C22H20Cl2F3NO5
Molecular Weight:
506.3
Pathway:
Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
Cl.CN1CC[C@H]([C@@H]1CO)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1Cl)C(F)(F)F
Target:
CDK

References

1. Dey J, et al. Voruciclib, a clinical stage oral CDK9 inhibitor, represses MCL-1 and sensitizes high-risk Diffuse Large B-cell Lymphoma to BCL2 inhibition. Sci Rep. 2017 Dec 21;7(1):18007.