TargetMol

Seviteronel racemate

Product Code:
 
TAR-T13313
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13313-5mg5mg£351.00
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Quantity:
TAR-T13313-50mg50mg£1,267.00
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Quantity:
TAR-T13313-100mg100mg£1,669.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Seviteronel racemate is the racemate form of Seviteronel and is a potent inhibitor of CYP17 lyase.
CAS:
1375603-36-3
Formula:
C18H17F4N3O3
Molecular Weight:
399.346
Purity:
0.98
SMILES:
CC(C)C(O)(c1c[nH]nn1)c1ccc2cc(OC(F)F)c(OC(F)F)cc2c1

References

1. Rafferty SW, et al. Highly-selective 4-(1,2,3-triazole)-based P450c17a 17,20-lyase inhibitors. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2444-7. 2. Sankar N. Maity, et al. Abstract 4772: Efficacy of VT-464, a novel selective inhibitor of cytochrome P450 17,20-lyase, in castrate-resistant prostate cancer models. Cancer Research: April 15, 2013; Volume 73, Issue 8, Supplement 1