TargetMol

VU 6008667

Product Code:
 
TAR-T13315
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13315-50mg50mg£962.00
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Quantity:
TAR-T13315-100mg100mg£1,564.00
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This product comes from: United States.
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Further Information

Bioactivity:
VU 6008667 is a selective negative allosteric M5 NAM modulator (IC50s: 1.2 μM and 1.6 μM for human M5 and rat M5, respectively).
CAS:
2092923-21-0
Formula:
C24H17ClF2N2O2
Molecular Weight:
438.86
Purity:
0.98
SMILES:
Cc1cc(ccc1Cl)[C@]12N(CCN1C(=O)c1ccccc21)C(=O)c1ccc(F)c(F)c1

References

1. McGowan KM et al, Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studies. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1356-1359.