TargetMol

AC260584

Product Code:
 
TAR-T14092
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14092-5mg5mg£335.00
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TAR-T14092-50mg50mg£1,267.00
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TAR-T14092-100mg100mg£1,669.00
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Further Information

Bioactivity:
AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6).
CAS:
560083-42-3
Formula:
C20H29FN2O2
Molecular Weight:
348.462
Purity:
0.98
SMILES:
CCCCC1CCN(CCCN2C(=O)COc3cc(F)ccc23)CC1

References

1. Bradley SR, et al. AC260584, an orally bioavailable M(1) muscarinic receptor allosteric agonist, improves cognitive performance in an animal model. Neuropharmacology. 2010 Feb;58(2):365-73. 2. Li Z, et al. AC260584 (4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one), a selective muscarinic M1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus. Eur J Pharmacol. 2007 Oct 31;572(2-3):129-37.