TargetMol

BAY-1316957

Product Code:
 
TAR-T14500
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14500-50mg50mg£704.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T14500-100mg100mg£1,099.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
BAY-1316957 is a highly potent and selective EP4 receptor antagonist. With an IC50 of 15.3 nM. Good oral bioavailability[1].
CAS:
1613264-40-6
Formula:
C27H27N3O3
Molecular Weight:
441.531
Pathway:
Immunology/Inflammation; GPCR/G Protein
Purity:
0.98
SMILES:
CCn1c2ccc(C)cc2c2cc(ccc12)-c1nc2c(C)c(ccc2n1CCOC)C(O)=O
Target:
Prostaglandin Receptor

References

1. B?urle S, et al. Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis. J Med Chem. 2019 Mar 14;62(5):2541-2563.