TargetMol

BMS-935177

Product Code:
 
TAR-T14681
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14681-10mg10mgEnquire
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TAR-T14681-50mg50mgEnquire
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TAR-T14681-1mg1mg£119.00
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TAR-T14681-2mg2mg£142.00
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TAR-T14681-5mg5mg£213.00
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TAR-T14681-1mL1 mL * 10 mM (in DMSO)£236.00
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Further Information

Bioactivity:
BMS-935177 is a reversible BTK inhibitor with IC50 value of 3 nM.
CAS:
1231889-53-4
Formula:
C31H26N4O3
Molecular Weight:
502.56
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9989
SMILES:
O=C(N)C1=CC=C(C=2C=CC=C(C2C)N3C=NC=4C=CC=CC4C3=O)C=5C6=CC=C(C=C6NC15)C(O)(C)C
Target:
BTK

References

De Lucca GV, et al. Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177). J Med Chem. 2016 Sep 8;59(17):7915-35.