TargetMol

HFI-142

Product Code:
 
TAR-T15479
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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This product comes from: United States.
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Further Information

Bioactivity:
HFI-142 is an inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 2.01 μM).
CAS:
332164-34-8
Formula:
C17H16N2O4
Molecular Weight:
312.325
Purity:
0.98
SMILES:
CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c1cccnc1

References

1. Albiston AL, et al. Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobicpacking point at the active site of insulin-regulated aminopeptidase. Mol Pharmacol. 2010 Oct;78(4):600-7.