TargetMol

KT185

Product Code:
 
TAR-T15668
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15668-50mg50mg£664.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T15668-100mg100mg£962.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
KT185 is an orally-bioavailable and brain-penetrant ABHD6 inhibitor (IC50: 0.21 nM in Neuro2A cells).
CAS:
1472640-86-0
Formula:
C32H33N5O2
Molecular Weight:
519.649
Purity:
0.98
SMILES:
O=C(N1CCCCC1)c1cccc(c1)-c1ccc(cc1)-c1cn(nn1)C(=O)N1CCCCC1c1ccccc1

References

1. Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of ?/?-hydrolase domain containing 6 (ABHD6). J Med Chem. 2013 Nov 14;56(21):8270-9.