TargetMol

LY3130481

Product Code:
 
TAR-T15814
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15814-5mg5mg£337.00
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TAR-T15814-50mg50mg£1,364.00
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Quantity:
TAR-T15814-100mg100mg£1,990.00
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This product comes from: United States.
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Further Information

Bioactivity:
LY3130481 is an AMPA receptor antagonist. It is dependent upon transmembrane AMPA receptor regulatory protein (TARP) γ-8 and selectively inhibits AMPA/TARP γ-8 (IC50: 65 nM).
CAS:
1610802-47-5
Formula:
C19H18N4O3S
Molecular Weight:
382.44
Purity:
0.98
SMILES:
C[C@H](c1ccn(n1)-c1ccc(OCCO)cn1)c1ccc2[nH]c(=O)sc2c1

References

1. Gardinier KM,et al. Discovery of the First ?-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) ?-8. J Med Chem. 2016 May 26;59(10):4753-68.