TargetMol

Melinamide

Product Code:
 
TAR-T16036
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T16036-100mg100mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Melinamide is an amide derivative of an unsaturated long-chain fatty acid and also is an inhibitor of cholesterol absorption (IC50: 20.9 μM).
CAS:
14417-88-0
Formula:
C26H41NO
Molecular Weight:
383.62
Purity:
0.98
SMILES:
CCCCCC=C/CC=C/CCCCCCCC(=O)NC(C)c1ccccc1

References

1. Kusunoki J, et al. Effect of F-1394, a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), on esterification of cholesterol and basolateral secretion of cholesteryl ester in Caco-2 cells Nihon Yakurigaku Zasshi. 1997 Dec;110(6):357-65. 2. Natori K, et al. Mechanism of the inhibition of cholesterol absorption by DL-melinamide: inhibition of cholesterol esterification. Jpn J Pharmacol. 1986 Dec;42(4):517-23. 3. Matsubara K, et al. Cholesterol-lowering effect of N-(alpha-methylbenzyl)linoleamide (melinamide) in cholesterol-fed diabetic rats. Atherosclerosis. 1988 Aug;72(2-3):199-204.