TargetMol

N-[(4-Aminophenyl)methyl]adenosine

Product Code:
 
TAR-T16166
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16166-50mg50mg£821.00
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TAR-T16166-100mg100mg£1,267.00
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Further Information

Bioactivity:
N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor (Ki: 29 nM for Rat ecto-5?-Nucleotidase).
CAS:
95523-13-0
Formula:
C17H20N6O4
Molecular Weight:
372.385
Pathway:
PI3K/Akt/mTOR signaling; Chromatin/Epigenetic
Purity:
0.98
SMILES:
Nc1ccc(CNc2ncnc3n(cnc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1
Target:
AMPK

References

1. Bhattarai S, et al. ?,?-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58(15):6248-63. 2. Chen JB, et al. Design and synthesis of novel dual-action compounds targeting the adenosine A(2A) receptor and adenosine transporter for neuroprotection. ChemMedChem. 2011 Aug 1;6(8):1390-400. 3. Zhu Z, et al. Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. Bioorg Med Chem. 2008 Apr 1;16(7):3848-65.