TargetMol

RIPK-IN-4

Product Code:
 
TAR-T16755
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T16755-5mg5mg£371.00
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Quantity:
TAR-T16755-50mg50mg£1,564.00
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Quantity:
TAR-T16755-100mg100mg£2,336.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
RIPK-IN-4 is an effective and selective inhibitor of RIPK2. It also has excellent oral bioavailability (IC50: 3 nM).
CAS:
2141969-56-2
Formula:
C18H21FN4O3S
Molecular Weight:
392.45
Pathway:
Apoptosis
Purity:
0.98
SMILES:
CCOc1cc2ncc(-c3cc(N)nc(F)c3)n2cc1S(=O)(=O)C(C)(C)C
Target:
TNF

References

1. He X, et al. Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett. 2017 Sep 27;8(10):1048-1053.