TargetMol

SB-772077B dihydrochloride

Product Code:
 
TAR-T16855
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16855-50mg50mg£703.00
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Quantity:
TAR-T16855-100mg100mg£970.00
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This product comes from: United States.
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Further Information

Bioactivity:
SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).
CAS:
607373-46-6
Formula:
C15H20Cl2N8O2
Molecular Weight:
415.28
Pathway:
Cytoskeletal Signaling; Cell Cycle/Checkpoint; Stem Cells
Purity:
0.98
SMILES:
Cl.Cl.CCn1c(nc2cncc(C(=O)N3CC[C@H](N)C3)c12)-c1nonc1N
Target:
ROCK

References

1. Doe C, et al. Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities. J Pharmacol Exp Ther. 2007 Jan;320(1):89-98.