TargetMol

NLRP3-IN-2

Product Code:
 
TAR-T3230
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3230-50mg50mg£103.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3230-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3230-100mg100mg£113.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3230-200mg200mg£132.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
It is a NLRP3 Inflammasome Inhibitor I.
CAS:
16673-34-0
Formula:
C16H17ClN2O4S
Molecular Weight:
368.83
Pathway:
Immunology/Inflammation; NF-κb
Purity:
0.9898
SMILES:
COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(N)(=O)=O
Target:
NOD-like Receptor (NLR); NOD

References

1. Baldwin, A., Brough, D., & Freeman, S. (2015). Inhibiting the Inflammasome: A Chemical Perspective.?Journal Of Medicinal Chemistry,?59(5), 1691-1710. doi: 10.1021/acs.jmedchem.5b01091 2. Marchetti, C., Chojnacki, J., Toldo, S., Mezzaroma, E., Tranchida, N., & Rose, S. et al. (2014). A Novel Pharmacologic Inhibitor of the NLRP3 Inflammasome Limits Myocardial Injury After Ischemia?Reperfusion in the Mouse.?Journal Of Cardiovascular Pharmacology,?63(4), 316-322. doi: 10.1097/fjc.202002020020200200020053