TargetMol

CAY10762

Product Code:
 
TAR-T36498
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36498-5mg5mg£850.00
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Quantity:
TAR-T36498-50mg50mg£1,661.00
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Quantity:
TAR-T36498-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
CAY10762 is an inhibitor of monoacylglycerol lipase (MAGL; IC50= 34.1 nM).1It reduces hydrogen peroxide-induced lactate dehydrogenase (LDH) release from Neuro2a cells when used at a concentration of 1 μM. CAY10762 (10 mg/kg) increases levels of 2-arachidonoyl glycerol in mouse brain.
CAS:
2514-37-6
Formula:
C15H13NOS
Molecular Weight:
255.3
Purity:
0.98
SMILES:
O=C1C2=CC=CC=C2SN1CCC3=CC=CC=C3

References

Castelli, R., Scalvini, L., Vacondio, F., et al.Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteinesJ. Med. Chem.63(3)1261-1280(2020)