TargetMol

Cdk2 Inhibitor II

Product Code:
 
TAR-T36933
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36933-1mg1mg£155.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T36933-5mg5mg£281.00
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TAR-T36933-10mg10mg£383.00
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TAR-T36933-25mg25mg£586.00
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TAR-T36933-50mg50mg£780.00
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Quantity:
TAR-T36933-100mg100mg£1,026.00
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Quantity:
TAR-T36933-500mg500mg£2,022.00
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Quantity:
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Further Information

Bioactivity:
The cyclin-dependent kinase 2 (Cdk2) works with cyclins A or E to regulate S phase and G2-M transition during the cell cycle. Cdk2 Inhibitor II is a 3-(benzylidne)indolin-2-one analog that selectively and potently inhibits Cdk2 (IC50 = 60 nM). It is cell permeable, reversible, and ATP-competitive.
CAS:
222035-13-4
Formula:
C14H11BrN4O3S
Molecular Weight:
395.23
Pathway:
Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
NS(=O)(=O)c1ccc(NN=C2/C(=O)Nc3ccc(Br)cc23)cc1
Target:
CDK

References

S T Davis, et al. Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science. 2001 Jan 5;291(5501):134-7.