TargetMol

Thalidomide-4-OH

Product Code:
 
TAR-T7763
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7763-500mg500mg£94.00
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Further Information

Bioactivity:
Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used to recruit of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) is a linker to form PROTACs
CAS:
5054-59-1
Formula:
C13H10N2O5
Molecular Weight:
274.232
Pathway:
PROTAC
Purity:
0.9959
SMILES:
Oc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Target:
Ligand for E3 Ligase

References

Marks MG, et al. Effects of putative hydroxylated thalidomide metabolites on blood vessel density in the chorioallantoic membrane (CAM) assay and on tumor and endothelial cell proliferation. Biol Pharm Bull. 2002 May;25(5):597-604.