TargetMol

NKP-1339

Product Code:
 
TAR-TQ0016
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0016-50mg50mg£1,267.00
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TAR-TQ0016-100mg100mg£1,669.00
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Further Information

Bioactivity:
NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.
CAS:
197723-00-5
Formula:
C14H12Cl4N4NaRu
Molecular Weight:
502.14
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
[Cl-][Ru+3]([N]1=CC2=CC=CC=C2N1)([Cl-])([Cl-])([N]3=CC4=CC=CC=C4N3)[Cl-].[Na+]
Target:
DNA/RNA Synthesis

References

Robert Trondl, et al. NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application. Chemical Science. Chemical Science