TargetMol

Bruceine D

Product Code:
 
TAR-TWS2045
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TWS2045-1mg1mg£103.00
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TAR-TWS2045-5mg5mg£143.00
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TAR-TWS2045-1mL1 mL * 10 mM (in DMSO)£151.00
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TAR-TWS2045-10mg10mg£173.00
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TAR-TWS2045-25mg25mg£243.00
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TAR-TWS2045-50mg50mg£326.00
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TAR-TWS2045-100mg100mg£447.00
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Further Information

Bioactivity:
1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW199 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.
CAS:
21499-66-1
Formula:
C20H26O9
Molecular Weight:
410.419
Pathway:
Stem Cells; Apoptosis; Neuroscience; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Purity:
0.9996
SMILES:
CC1=CC(=O)[C@@H](O)[C@@]2(C)[C@H]1C[C@H]1OC(=O)[C@H](O)[C@@]3(O)[C@]4(C)OC[C@]13[C@@H]2[C@@H](O)[C@@H]4O
Target:
Apoptosis; Antiviral; Gamma-secretase; Parasite

References

Liu L , Lin Z X , Leung P S , et al. Involvement of the mitochondrial pathway in bruceine D-induced apoptosis in Capan-2 human pancreatic adenocarcinoma cells.[J]. International Journal of Molecular Medicine, 2012, 30(1):93.