TargetMol

Glafenine Hydrochloride

Product Code:
 
TAR-T0055L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0055L-50mg50mg£97.00
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TAR-T0055L-100mg100mg£109.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T0055L-1mL1 mL * 10 mM (in DMSO)£114.00
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This product comes from: United States.
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Further Information

Bioactivity:
Glafenine Hydrochloride is an anti-inflammatory agent.
CAS:
65513-72-6
Formula:
C19H18Cl2N2O4
Molecular Weight:
409.26
Pathway:
Membrane transporter/Ion channel
Purity:
0.9891
SMILES:
Cl.OCC(O)COC(=O)c1ccccc1Nc1ccnc2cc(Cl)ccc12
Target:
ABC

References

1. Zhang Y, et al. Identification of inhibitors of ABCG2 by a bioluminescence imaging-based high-throughput assay. Cancer Res. 2009 Jul 15;69(14):5867-75. 2. Robert R, et al. Correction of the Delta phe508 cystic fibrosis transmembrane conductance regulator trafficking defect by the bioavailable compound glafenine. Mol Pharmacol. 2010 Jun;77(6):922-30. 3. Goldsmith, J., Cocchiaro, J., Rawls, J., & Jobin, C. (2012). Glafenine-induced intestinal injury in zebrafish is ameliorated by ?-opioid signaling via enhancement of Atf6-dependent cellular stress responses.?Disease Models & Mechanisms,?6(1), 146-159. doi: 10.1242/dmm.009852