TargetMol

Nicotinamide N-oxide

Product Code:
 
TAR-T0617
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0617-50mg50mg£97.00
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TAR-T0617-100mg100mg£109.00
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TAR-T0617-1mL1 mL * 10 mM (in DMSO)£111.00
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Further Information

Bioactivity:
Nicotinamide N-oxide is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of nicotinamide N-oxide to nicotinamide in the liver is xanthine oxidase.
CAS:
1986-81-8
Formula:
C6H6N2O2
Molecular Weight:
138.126
Pathway:
GPCR/G Protein; Autophagy; Immunology/Inflammation; Cell Cycle/Checkpoint; Metabolism
Purity:
0.999
SMILES:
NC(=O)c1ccc[n+]([O-])c1
Target:
c-Myc; Endogenous Metabolite; CXCR; Drug Metabolite

References

1. Cutshall NS, et al. Nicotinamide N-oxides as CXCR2 antagonists. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1951-4. 2. Real AM, et al. Nicotinamide N-oxidation by CYP2E1 in human liver microsomes. Drug Metab Dispos. 2013 Mar;41(3):550-3.