TargetMol

ABT-418 hydrochloride

Product Code:
 
TAR-T10224
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
ABT-418 hydrochloride is a selective agonist of nAChRs with cognitive enhancing and anxiolytic activities. It activates cholinergic channel and can be used for the research of Alzheimer's disease.
CAS:
147388-83-8
Formula:
C9H15ClN2O
Molecular Weight:
202.68
Purity:
0.98
SMILES:
Cl.CN1CCC[C@H]1c1cc(C)no1

References

1. Brioni JD, et al. Anxiolytic-like effects of the novel cholinergic channel activator ABT-418. J Pharmacol Exp Ther. 1994 Oct;271(1):353-61. 2. Guo T, et al. A comparative study of the effects of ABT-418 and methylphenidate on spatial memory in an animal model of ADHD. Neurosci Lett. 2012 Oct 18;528(1):11-5.