TargetMol

Prazosin hydrochloride

Product Code:
 
TAR-T1050
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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TAR-T1050-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T1050-100mg100mg£111.00
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Further Information

Bioactivity:
Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin Hydrochloride is a synthetic piperazine derivative with hypotensive antiadrenergic properties, It is used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention.
CAS:
19237-84-4
Formula:
C19H22ClN5O4
Molecular Weight:
419.87
Pathway:
Neuroscience; Autophagy; Membrane transporter/Ion channel; Immunology/Inflammation; GPCR/G Protein
Purity:
0.9987
SMILES:
Cl.COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1
Target:
Potassium Channel; MRP; Adrenergic Receptor; ABC; Autophagy

References

1. Baum O, et al. Am J Physiol Heart Circ Physiol,2004, 287(5), H2300-H2308. 2. Donoso MV, et al. J Pharmacol Exp Ther,1997, 282(2), 691-698. 3. L? AD, et al. Psychopharmacology (Berl),2011, 218(1), 89-99. 4. Wadenberg ML, et al. J Neural Transm, 2000, 107(10), 1229-1238. 5. Math? JM, et al. Eur J Pharmacol,1996, 309(1), 1-11. 6. Bowden G D, Land K M, O'Connor R M, et al. High-throughput screen of drug repurposing library identifies inhibitors of Sarcocystis neurona growth[J]. International Journal for Parasitology: Drugs and Drug Resistance. 2018 Apr?8(1): 137-144.