TargetMol

DMU2105

Product Code:
 
TAR-T11065
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
DMU2105 is a potent and specific CYP1B1 inhibitor, with IC50s of 10 nM and 742 nM for CYP1B1 and CYP1A1, respectively.
CAS:
1821143-79-6
Formula:
C18H13NO
Molecular Weight:
259.3
Pathway:
Metabolism
Purity:
0.98
SMILES:
O=C(C1=CC=CN=C1)/C=C/C2=CC=C3C=CC=CC3=C2.[(E)]
Target:
P45

References

1. Horley NJ, et al. Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines. Eur J Med Chem. 2017 Mar 31;129:159-174.