TargetMol

Indirubin Derivative E804

Product Code:
 
TAR-T11654
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Indirubin Derivative E804 is an effective inhibitor of IGF1R, which has an IC50 value of 0.65.
CAS:
854171-35-0
Formula:
C20H19N3O4
Molecular Weight:
365.389
Purity:
0.98
SMILES:
OCC(O)CCON=C1/C(/Nc2ccccc/12)=C1/C(=O)Nc2ccccc12

References

1. Cheng X, et al. Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule. J Med Chem. 2017 Jun 22;60(12):4949-4962.