TargetMol

LTβR-IN-1

Product Code:
 
TAR-T11886
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11886-1mg1mg£111.00
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TAR-T11886-5mg5mg£168.00
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TAR-T11886-1mL1 mL * 10 mM (in DMSO)£177.00
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TAR-T11886-10mg10mg£229.00
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TAR-T11886-25mg25mg£381.00
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TAR-T11886-50mg50mg£533.00
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TAR-T11886-100mg100mg£732.00
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TAR-T11886-500mg500mg£1,420.00
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This product comes from: United States.
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Further Information

Bioactivity:
LTβR-IN-1 is potent in TWEAK-stimulated p52 translocation assays with an IC50 of 10 μM and did not alter TNF-α?induced p65 nuclear translocation. LTβR-IN-1 is a potent, selective lymphotoxin β receptor (LTβR) inhibitor with an IC50 of 10 μM.
CAS:
2189366-77-4
Formula:
C18H16N4O2
Molecular Weight:
320.352
Pathway:
NF-κb|Others|Immunology/Inflammation
Purity:
0.98
SMILES:
C[C@@H](N1Cc2ccccc2C1=O)C(=O)Nc1nc2ccccc2[nH]1
Target:
LTR|Others|NF-κB

References

1. Henry KL, et al. CDK12-mediated transcriptional regulation of noncanonical NF-?B components is essential for signaling. Sci Signal. 2018 Jul 31;11(541).