TargetMol

NSC23925

Product Code:
 
TAR-T16352
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).
CAS:
858474-14-3
Formula:
C22H26Cl2N2O2
Molecular Weight:
421.36
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
Cl.Cl.COc1ccc(cc1)-c1cc(C(O)C2CCCCN2)c2ccccc2n1
Target:
Nrf2

References

1. Yang X, et al. Nsc23925 prevents the development of paclitaxel resistance by inhibiting the introduction of P-glycoprotein and enhancing apoptosis. Int J Cancer. 2015 Oct 15;137(8):2029-39. 2. Duan Z, et al. NSC23925, identified in a high-throughput cell-based screen, reverses multidrug resistance. PLoS One. 2009 Oct 12;4(10):e7415.