TargetMol

PF-05180999

Product Code:
 
TAR-T16484
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T16484-100mg100mgEnquire
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TAR-T16484-50mg50mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
PF-05180999 is an inhibitor of phosphodiesterase 2A (IC50: 1.6 nM).
CAS:
1394033-54-5
Formula:
C19H17F3N8
Molecular Weight:
414.396
Pathway:
Metabolism
Purity:
0.98
SMILES:
Cc1nc(-c2cnn(C)c2-c2ccc(cn2)C(F)(F)F)c2c(ncnn12)N1CCC1
Target:
PDE

References

1. Helal CJ, et al. Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate. J Med Chem. 2018 Feb 8;61(3):1001-1018.