Rifalazil

Product Code:

TAR-T16749

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

No additional charges, what you see is what you pay! *

Code	Size	Price

TAR-T16749-100mg

100mg

Enquire

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

TAR-T16749-50mg

50mg

Enquire

Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.

Quantity:

Prices exclude any Taxes / VAT

How to order with us Contact us

Further Information

Bioactivity:

Rifalazil is a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase. Rifalazil is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis (MIC: 0.00025 to 0.0025 μg/ml).

CAS:

129791-92-0

Formula:

C51H64N4O13

Molecular Weight:

941.088

Pathway:

Cell Cycle/Checkpoint; DNA Damage/DNA Repair

Purity:

0.98

SMILES:

CO[C@H]1C=C/O[C@@]2(C)Oc3c(C2=O)c2c4nc5c(O)cc(cc5oc4c(NC(=O)C(C)=C/C=C[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(=O)c2c(O)c3C)N1CCN(CC(C)C)CC1

Target:

DNA/RNA Synthesis

Documents

References

1. Suchland RJ, et al. Rifalazil pretreatment of mammalian cell cultures prevents subsequent Chlamydia infection.Antimicrob Agents Chemother. 2006 Feb;50(2):439-44. 2. Shoen CM, et al. Evaluation of rifalazil in long-term treatment regimens for tuberculosis in mice.Antimicrob Agents Chemother.?2000 Jun;44(6):1458-62. 3. Rothstein DM, et al. Development potential of rifalazil.Expert Opin Investig Drugs. 2003 Feb;12(2):255-71.