TargetMol

Omeprazole Sodium

Product Code:
 
TAR-T22391
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T22391-100mg100mg£103.00
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TAR-T22391-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T22391-200mg200mg£117.00
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TAR-T22391-500mg500mg£148.00
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This product comes from: United States.
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Further Information

Bioactivity:
Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole Sodium inhibits growth of Gram-positive and Gram-negative bacteria.
CAS:
95510-70-6
Formula:
C17H18N3NaO3S
Molecular Weight:
367.4
Pathway:
Microbiology/Virology; Membrane transporter/Ion channel; Metabolism; Autophagy
Purity:
0.98
SMILES:
COC1=CC2=C(C=C1)[N]([Na])C(=N2)[S](=O)CC3=NC=C(C)C(=C3C)OC
Target:
P45; Proton pump; Antibacterial; Autophagy

References

1. Jonkers D, et al. Omeprazole inhibits growth of gram-positive and gram-negative bacteria including Helicobacter pylori in vitro. J Antimicrob Chemother. 1996 Jan;37(1):145-50. 2. Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330. 3. Li XQ, et al. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos. 2004 Aug;32(8):821-7.