TargetMol

10-Cl-BBQ

Product Code:
 
TAR-T24960
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24960-5mg5mg£850.00
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Quantity:
TAR-T24960-50mg50mg£1,661.00
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Quantity:
TAR-T24960-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
10-Cl-BBQ is a ligand of aryl hydrocarbon receptor (AhR).
CAS:
23982-76-5
Formula:
C18H9ClN2O
Molecular Weight:
304.73
Purity:
0.98
SMILES:
Clc1ccc2nc3c4cccc5cccc(c45)c(=O)n3c2c1

References

1. Ehrlich AK, Pennington JM, Wang X, Rohlman D, Punj S, L?hr CV, Newman MT, Kolluri SK, Kerkvliet NI. Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice. J Immunol. 2016 Jan 1;196(1):264-73. doi: 10.4049/jimmunol.1501789. Epub 2015 Nov 16. PubMed PMID: 26573835; PubMed Central PMCID: PMC4684970. 2. Punj S, Kopparapu P, Jang HS, Phillips JL, Pennington J, Rohlman D, O'Donnell E, Iversen PL, Kolluri SK, Kerkvliet NI. Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease. PLoS One. 2014 Feb 19;9(2):e88726. doi: 10.1371/journal.pone.0088726. eCollection 2014. PubMed PMID: 24586378; PubMed Central PMCID: PMC3929365.