TargetMol

NSC-668036

Product Code:
 
TAR-T28211
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28211-5mg5mg£390.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28211-50mg50mg£1,299.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T28211-100mg100mg£1,942.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
NSC-668036 is an inhibitor of Dishevelled (Dvl) protein, a key protein in wnt signaling.
CAS:
144678-63-7
Formula:
C21H36N2O9
Molecular Weight:
460.524
Purity:
0.98
SMILES:
CC(C)C(O)C(=O)N([C@@H](C)C(=O)O[C@@H](C(C)C)C(O)=O)C(=O)[C@H](C)NC(=O)OC(C)(C)C

References

1. Wang C, Dai J, Sun Z, Shi C, Cao H, Chen X, Gu S, Li Z, Qian W, Han X. Targeted inhibition of disheveled PDZ domain via NSC668036 depresses fibrotic process. Exp Cell Res. 2015 Feb 1;331(1):115-22. doi: 10.1016/j.yexcr.2014.10.023. Epub 2014 Nov 5. PubMed PMID: 25445788. 2. Chen X, Deng Y. Simulations of a specific inhibitor of the dishevelled PDZ domain. J Mol Model. 2009 Jan;15(1):91-6. doi: 10.1007/s00894-008-0377-x. Epub 2008 Oct 25. PubMed PMID: 18953581. 3. Shan J, Shi DL, Wang J, Zheng J. Identification of a specific inhibitor of the dishevelled PDZ domain. Biochemistry. 2005 Nov 29;44(47):15495-503. PubMed PMID: 16300398.