TargetMol

4-hydroxyphenylacetic acid

Product Code:
 
TAR-T3743
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3743-100mg100mg£103.00
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Quantity:
TAR-T3743-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T3743-200mg200mg£117.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
4-hydroxyphenylacetic acid is a major microbiota-derived metabolite of polyphenols. 4-hydroxyphenylacetic acid is involved in the antioxidative action. 4-hydroxyphenylacetic acid induces expression of Nrf2.
CAS:
156-38-7
Formula:
C8H8O3
Molecular Weight:
152.149
Pathway:
Metabolism; Immunology/Inflammation; oxidation-reduction
Purity:
0.991
SMILES:
OC(=O)Cc1ccc(O)cc1
Target:
Antioxidant; Nrf2; Endogenous Metabolite

References

An S, Yao Y, Wu J, et al.Gut-derived 4-hydroxyphenylacetic acid attenuates sepsis-induced acute kidney injury by upregulating ARC to inhibit necroptosis.Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease.2024, 1870(1): 166876. Zhao H, et al. 4-Hydroxyphenylacetic Acid Prevents Acute APAP-Induced Liver Injury by Increasing Phase IIand Antioxidant Enzymes in Mice. Front Pharmacol. 2018 Jun 19;9:653.