TargetMol

pNPS-DHA

Product Code:
 
TAR-T38127
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38127-5mg5mg£850.00
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Quantity:
TAR-T38127-50mg50mg£1,661.00
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Quantity:
TAR-T38127-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1It inhibits degranulation of RBL-2H3 mast cells (IC50= 15 μM).pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice.
CAS:
2454246-25-2
Formula:
C28H36N2O5S
Molecular Weight:
512.7
Purity:
0.98
SMILES:
CC/C=CC/C=CC/C=CC/C=CC/C=CC/C=CCCC(NS(C1=CC=C([N+]([O-])=O)C=C1)(=O)=O)=O

References

Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)