TargetMol

GLYCODEOXYCHOLIC ACID

Product Code:
 
TAR-T5352
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5352-100mg100mg£104.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T5352-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells.
CAS:
360-65-6
Formula:
C26H43NO5
Molecular Weight:
449.632
Pathway:
; Metabolism
Purity:
1
SMILES:
C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
Target:
Endogenous Metabolite

References

CHEN Jiang, et al. The effect of glycodeoxycholic acid on P53 expression in the apoptosis of SMMC-7721 cells. Chinese Journal of Clinical Laboratory Science, 2009, 27(3):167-169. Woolbright BL, et al. Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients. Toxicol Sci. 2014 Dec;142(2):436-44. Qiu Q, Guo G, Guo X, et al.P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.Biomedicines.2023, 11(3): 882.