TargetMol

Thalidomide-O-amido-PEG3-C2-NH2 TFA

Product Code:
 
TAR-T7758
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7758-5mg5mg£111.00
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TAR-T7758-10mg10mg£125.00
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TAR-T7758-1mL1 mL * 10 mM (in DMSO)£132.00
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TAR-T7758-25mg25mg£148.00
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TAR-T7758-50mg50mg£209.00
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TAR-T7758-100mg100mg£321.00
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Further Information

Bioactivity:
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
CAS:
1957236-21-3
Formula:
C25H31F3N4O11
Molecular Weight:
620.535
Pathway:
Others|PROTAC
Purity:
0.9982
SMILES:
OC(=O)C(F)(F)F.NCCOCCOCCOCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Target:
E3 Ligase Ligand-Linker Conjugate|Ligand for E3 Ligase|Others

References

BRADNER, James, et al. METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES. WO2017024317A2.