TargetMol

Fingolimod

Product Code:
 
TAR-T7939
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7939-100mg100mg£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7939-1mL1 mL * 10 mM (in DMSO)£113.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7939-500mg500mg£172.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T7939-1g1g£197.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Fingolimod is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).
CAS:
162359-55-9
Formula:
C19H33NO2
Molecular Weight:
307.478
Pathway:
Cytoskeletal Signaling; GPCR/G Protein
Purity:
0.9976
SMILES:
CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1
Target:
S1P Receptor; PAK; LPL Receptor

References

Wang X, Li X, Wang J, et al. SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion. Journal of Cell Biology. 2022, 221(7): e202111125 Zhang T, Wang Y, Li Q, et al. Mesenchymal stromal cells equipped by IFN? empower T cells with potent anti-tumor immunity. Oncogene. 2022: 1-16. Szepanowski, Fabian, Derksen, Angelika, Steiner, Irina,et al. Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling[J]. Journal of Neuroinflammation, 13(1):143. Amelioration of colitis through blocking lymphocytes entry to Peyer's patches by sphingosine?1?phosphate lyase inhibitor[J]. Journal of Gastroenterology & Hepatology, 2018, 33(9).