TargetMol

Coumarin-3-carboxylic acid

Product Code:
 
TAR-TJS0339
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TJS0339-1mL1 mL * 10 mM (in DMSO)£94.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TJS0339-500mg500mg£109.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
The combination of Valproic acid with coumarin-3-carboxylic acid suppresses the proliferation and migration of lung cancer cells via EGFR/VEGFR2/c-Met-Akt-NF-κB signaling pathways; this combination may have a wide therapeutic and/or adjuvant therapeutic application in the treatment of lung cancer.
CAS:
531-81-7
Formula:
C10H6O4
Molecular Weight:
190.154
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9976
SMILES:
OC(=O)c1cc2ccccc2oc1=O
Target:
VEGFR

References

Xin Liu, et al. Enhanced suppression of proliferation and migration in highly-metastatic lung cancer cells by combination of valproic acid and coumarin-3-carboxylic acid and its molecular mechanisms of action. Cytotechnology. 2013 Aug; 65(4): 597?608.