TargetMol

EIPA hydrochloride

Product Code:
 
TAR-T11172
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM.
CAS:
1345839-28-2
Formula:
C11H19Cl2N7O
Molecular Weight:
336.22
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
Cl.CCN(C(C)C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N
Target:
TRP/TRPV Channel

References

1. Dai XQ, et al. Inhibition of TRPP3 channel by MK-870 and analogs. Mol Pharmacol. 2007 Dec;72(6):1576-85. 2. Shi H, et al. Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells. Cell Physiol Biochem. 2017;42(6):2418-2429. 3. Zhu BY, et al. A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis.