TargetMol

Mofegiline hydrochloride

Product Code:
 
TAR-T12088
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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This product comes from: United States.
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Further Information

Bioactivity:
Mofegiline hydrochloride is a potent and selective enzyme-activated irreversible MAO-B inhibitor.
CAS:
120635-25-8
Formula:
C11H14ClF2N
Molecular Weight:
233.69
Purity:
0.98
SMILES:
Cl.NCC(CCc1ccc(F)cc1)=CF

References

1. Zreika M, et al. MDL 72,974: a potent and selective enzyme-activated irreversible inhibitor of monoamine oxidase type B with potential for use in Parkinson's disease. J Neural Transm Park Dis Dement Sect. 1989;1(4):243-54. 2. Yu PH, et al. Inhibition of a type B monoamine oxidase inhibitor, (E)-2-(4-fluorophenethyl)-3-fluoroallylamine (MDL-72974A), on semicarbazide-sensitive amine oxidases isolated from vascular tissues and sera of different species. Biochem Pharmacol. 1992 Jan 22;43(2):307-12. 3. Dow J, et al. Novel carbamate metabolites of mofegiline, a primary amine monoamine oxidase B inhibitor, in dogs and humans. Drug Metab Dispos. 1994 Sep-Oct;22(5):738-49.