TargetMol

PNU109291

Product Code:
 
TAR-T28431
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28431-5mg5mg£1,091.00
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TAR-T28431-50mg50mg£2,143.00
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Quantity:
TAR-T28431-100mg100mg£2,801.00
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This product comes from: United States.
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Further Information

Bioactivity:
PNU109291 is a potent and selective 5-HT1D receptor agonist. PNU109291 reduces dural plasma extravasation evoked by trigeminal ganglion stimulation.
CAS:
187665-60-7
Formula:
C24H31N3O3
Molecular Weight:
409.53
Purity:
0.98
SMILES:
CNC(=O)c1ccc2[C@H](CCN3CCN(CC3)c3ccc(OC)cc3)OCCc2c1

References

1. Watts SW, Darios ES, Seitz BM, Thompson JM. 5-HT is a potent relaxant in rat superior mesenteric veins. Pharmacol Res Perspect. 2015 Feb;3(1):e00103. doi: 10.1002/prp2.103. Epub 2015 Jan 5. PubMed PMID: 25692021; PubMed Central PMCID: PMC4317234. 2. Jeong HJ, Mitchell VA, Vaughan CW. Role of 5-HT(1) receptor subtypes in the modulation of pain and synaptic transmission in rat spinal superficial dorsal horn. Br J Pharmacol. 2012 Mar;165(6):1956-65. doi: 10.1111/j.1476-5381.2011.01685.x. PubMed PMID: 21950560; PubMed Central PMCID: PMC3372843.