TargetMol

G-418 disulfate

Product Code:
 
TAR-T6512
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6512-500mg500mg£104.00
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Quantity:
TAR-T6512-1g1g£111.00
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This product comes from: United States.
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Further Information

Bioactivity:
G-418 (disulfate) is an aminoglycoside antibiotic, which blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
CAS:
108321-42-2
Formula:
C20H44N4O18S2
Molecular Weight:
692.7
Pathway:
Microbiology/Virology
Purity:
0.999
SMILES:
OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O
Target:
Antibacterial; Antibiotic

References

Cheng G, An F, Cao Z, et al.DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway.European Journal of Histochemistry.2023, 67(1). Murphy NB, et al. Antimicrob Agents Chemother, 1993, 37(5), 1167-1170. Ye G, Huang M, Li Y, et al. The FAP?-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway. Acta Pharmaceutica Sinica B. 2021 Yan R, Xie E, Li Y, et al. The structure of erastin-bound xCT?4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis. Cell Research. 2022-32?7?P1-4 Wang W, Zhang M, Huang Z, et al. Knockdown of CXCL5 inhibits the invasion, metastasis and stemness of bladder cancer lung metastatic cells by downregulating CD44. Anti-Cancer Drugs. 2022, 33(1): e103-e112. Li Y, et al. World J Gastroenterol, 2003, 9(10), 2174-2177. Davies J, et al. Am J Trop Med Hyg, 1980, 29(5 Suppl), 1089-1092 Shao C S, Zhou X H, Miao Y H, et al. In-situ observation of mitochondrial biogenesis as the early event of apoptosis[J]. bioRxiv. 2021: 2020.08. 23.263152. Shao C S, Zhou X H, Miao Y H, et al. In situ observation of mitochondrial biogenesis as the early event of apoptosis. Iscience. 2021, 24(9): 103038 Wang W, Zhang M, Huang Z, et al. Knockdown of CXCL5 inhibits the invasion, metastasis and stemness of bladder cancer lung metastatic cells by downregulating CD44. Anti-Cancer Drugs. 2022, 33(1): e103-e112. Shao C S, Zhou X H, Miao Y H, et al. In-situ observation of mitochondrial biogenesis as the early event of apoptosis. Iscience. 2021, 24(9): 103038.