TargetMol

Trichlormethiazide

Product Code:
 
TAR-T0114
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0114-500mg500mg£107.00
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Quantity:
TAR-T0114-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T0114-1g1g£113.00
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Further Information

Bioactivity:
Trichlormethiazide is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.
CAS:
133-67-5
Formula:
C8H8Cl3N3O4S2
Molecular Weight:
380.64
Pathway:
Membrane transporter/Ion channel; Metabolism
Purity:
0.9932
SMILES:
NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl
Target:
ATPase; Carbonic Anhydrase

References

1. Temperini C, et al. Bioorg Med Chem. 2009 Feb 1;17(3):1214-21.