TargetMol

Losartan potassium

Product Code:
 
TAR-T0215
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T0215-500mg500mg£107.00
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Quantity:
TAR-T0215-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T0215-1g1g£113.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Losartan, an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.
CAS:
124750-99-8
Formula:
C22H22ClKN6O
Molecular Weight:
461.01
Pathway:
Endocrinology/Hormones
Purity:
1
SMILES:
[K+].CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[n-]1
Target:
RAAS

References

1. Burnier, M. Angiotensin II type 1 receptor blockers. Circulation, 2001. 103(6): p. 904-12. 2. Ashry, O., et al. Evidence for expression and function of angiotensin II receptor type 1 in pulmonary epithelial cells. Respir Physiol Neurobiol, 2014. 3. Choi, C.H., et al. Angiotensin II type I receptor and miR-155 in endometrial cancers: synergistic antiproliferative effects of anti-miR-155 and losartan on endometrial cancer cells. Gynecol Oncol, 2012. 126(1): p. 124-31. 4. Strawn WB, et al. Circulation, 2000, 101(13), 1586-1593. 5. Habashi JP, et al. Science, 2006, 312(5770), 117-121.