TargetMol

5-Aminosalicylic Acid

Product Code:
 
TAR-T0646
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0646-500mg500mg£107.00
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Further Information

Bioactivity:
Mesalamine is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.
CAS:
89-57-6
Formula:
C7H7NO3
Molecular Weight:
153.137
Pathway:
Neuroscience; Metabolism; DNA Damage/DNA Repair; Cytoskeletal Signaling; Immunology/Inflammation; NF-κb
Purity:
0.9788
SMILES:
Nc1ccc(O)c(c1)C(O)=O
Target:
NF-κB; Lipoxygenase; COX; Glutathione Peroxidase; Endogenous Metabolite; PAK; PPAR

References

1. Egan LJ, et al. J Biol Chem,1999, 274(37), 26448-26453. 2. Khare V, et al. Biochem Pharmacol,2013, 85(2), 234-244. 3. Das KK, et al. Mol Pharmacol,2009, 76(1), 183-191. 4. Khare V, et al. Biochem Pharmacol,2014, 87(2), 312-320. 5. Graham PM, et al. Mol Cell Biochem,2013, 378(1-2), 291-298. 6. Dammann K, et al. PAK1 modulates a PPAR?/NF-?B cascade in intestinal inflammation. Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2349-60.