TargetMol

Trimethoprim

Product Code:
 
TAR-T1153
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1153-500mg500mg£107.00
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Further Information

Bioactivity:
Trimethoprim is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.
CAS:
738-70-5
Formula:
C14H18N4O3
Molecular Weight:
290.323
Pathway:
DNA Damage/DNA Repair; Microbiology/Virology; Cell Cycle/Checkpoint; Metabolism
Purity:
0.9988
SMILES:
COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
Target:
DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic

References

1. Vouloumanou EK, et al. Int J Antimicrob Agents, 2011, 38(3), 197-216. 2. Cribb AE, et al. Adverse Drug React Toxicol Rev, 1996, 15(1), 9-50.