TargetMol

Sulindac sulfide

Product Code:
 
TAR-T13037
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13037-50mg50mgEnquire
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TAR-T13037-10mg10mg£95.00
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TAR-T13037-25mg25mg£109.00
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TAR-T13037-1mL1 mL * 10 mM (in DMSO)£134.00
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This product comes from: United States.
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Further Information

Bioactivity:
Sulindac sulfide is an inhibitor of noncompetitive γ-secretase(IC50 of 20.2 μM for γ42-secretase activity).
CAS:
49627-27-2
Formula:
C20H17FO2S
Molecular Weight:
340.41
Pathway:
MAPK|Others|Neuroscience
Purity:
0.98
SMILES:
O=C(O)CC(C1=C/2C=CC(F)=C1)=C(C)C2=CC3=CC=C(SC)C=C3
Target:
Others|AChR|Raf

References

1. Takahashi Y, et al. Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation. J Biol Chem. 2003 May 16;278(20):18664-70.