TargetMol

Praziquantel

Product Code:
 
TAR-T1435
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1435-500mg500mg£107.00
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Further Information

Bioactivity:
Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.
CAS:
55268-74-1
Formula:
C19H24N2O2
Molecular Weight:
312.413
Pathway:
Metabolism; Membrane transporter/Ion channel; Microbiology/Virology
Purity:
0.9986
SMILES:
O=C(C1CCCCC1)N1CC2N(CCc3ccccc23)C(=O)C1
Target:
Calcium Channel; Antibiotic; Parasite

References

1. Doenhoff MJ, et al. Curr Opin Infect Dis. 2008 Dec;21(6):659-67.